Originally Answered: My 4 month old daughter got her shots and has a big bump in her leg, she seems irritable, what should i do?
That could be an abscess.
You should have a copy of the patient information for all the vaccines given and it would tell you what side effects need medical attention.
Also you and your doctor are legally obligated to report ALL vaccine side effects. Without accurate reporting of side effects no one can make an educated decision about vaccination. Vaccines have been recalled because they are causing high rates of abscess due to contamination during production or improper administration. The faster these problems are reported the faster the problem is found and the less children are effected.
Sterile abscesses have occurred at the site of injection of certain inactivated vaccines. These abscesses presumably result from an inflammatory response to the vaccine or its adjuvant; in some instances, these reactions may be caused by inadvertent subcutaneous inoculation of a vaccine intended for intramuscular use. Administration of bacille Calmette-Guérin (BCG) vaccine often is followed by occurrence of local cysts, abscesses, and/or regional lymphadenopathy that will resolve spontaneously (see Tuberculosis).
Mild Problems (Common)
• Fever (up to about 1 child in 4)
• Redness or swelling where the shot was given (up to
about 1 child in 4)
• Soreness or tenderness where the shot was given (up
to about 1 child in 4)
The following mild problems have been reported:
• Soreness where the shot was given (up to about 1
person in 4).
• Redness, warmth, or swelling
where the shot was given
(up to 1/4 of children)
Reports of abscesses after the use of diphtheria and tetanus toxoids and pertussis vaccine (DTP vaccine) from two different lots (No. 1 and 2) of a single manufacturer (manufacturer A) prompted an investigation into the rates of abscess formation following the use of DTP vaccine from several different manufacturers. A total of 74 abscesses for lot 1, 16 for lot 2, and three for other DTP products was uncovered. The overall rate after lots 1 and 2 was 1.1 per 1,000 doses administered compared with 0.01 per 1,000 doses for DTP vaccine from other manufacturers (P less than .0001). Faulty technique, site and route of inoculation, microbiologic contamination, and hypersensitivity were ruled out as likely explanations for the increase in abscesses among recipients of DTP vaccine from manufacturer A. Use of a single needle to withdraw vaccine from the vial and to inoculate the vaccinees, combined with high aluminum adjuvant content in the implicated vaccine, may have led to an increased rate of abscess formation.
The recall involves 10 lots of its Hib vaccine, PedvaxHIB, and two of a Hib-hepatitis B combination vaccine, COMVAX, produced at its plant in West Point, Penn. Michael Thomas, Merck's vice president for vaccines, said that during routine testing, the company found the equipment used to make the vaccine was not fully sterilized. "We've not found any contamination in the vaccine," he said, and no reports of children harmed.
Children who already have received the recalled vaccine won't need follow-up care, Schuchat said. If the vaccine were to cause health problems, there probably would be swelling or an abscess at the injection site within a week of immunization.